Abstract:
Background Even though trust is placed at the central point in ensuring proper functioning of the health systems,
studies remain scant on how it afects both the implementation and uptake of COVID-19 response measures in lowand middle-income countries such as Tanzania. This study, therefore, explored the role of trust in the implementation
and uptake of recommended COVID-19 response measures including vaccines from the perspective of health professionals in Tanzania.
Methods This cross-sectional qualitative study was implemented in four of Tanzania’s thirty-one regions. Qualitative
data was collected through 26 in-depth interviews held with regional and district disease outbreak response teams,
district cold chain co-ordinators and health facility in-charges. In addition, fve focus group discussions and seven
group interviews were conducted with healthcare workers from the lower-level health facilities. Thematic analysis
was conducted and applied the trust constructs.
Results Interpersonal trust and health system trust emerged as two major themes in the study. Interpersonal trust was reported to stem from lack of transparency that instigated fear, worries, and confusion regarding the implementation and uptake of the recommended response measures. The distrust was mainly between health professionals
in health facilities and those assigned to isolation centres as well as between patients and community members. On the other hand, the health system trust was shaped by mixed feelings regarding COVID-19 vaccine national decisions, and conficting messages from national of cials, politicians and religious leaders on COVID-19 responses, safety,
and efectiveness of the vaccines. Questions surrounding the short duration of clinical trials, indeterminate postvaccination protection duration, impotence-linked beliefs, freemasonry notion and unclear vaccinated cards information are other reported contributory factors to mistrust in the health system. However, after a comprehensive health
education and experience in COVID-19 vaccination administration most professionals afrmed the efectiveness of the vaccines in limiting infections and its severe consequences.
Conclusion Participants indicated limited trust at both interpersonal and health system levels aggravated by lack of transparency, unclear and conficting messages on COVID-19 infections and response measures. Enforced transparency on pandemics alongside standardised messages from the reliable sources is crucial in enhancing trust
in implementation and uptake of the recommended response measures.